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Unlike many peptides that have only injectable research data, GHK-Cu has been tested in published human clinical trials specifically as a topical application with outcomes that compared favorably against gold-standard actives
Magnesium works through osmotic draw and mild smooth muscle stimulation, which complements natural peristalsis without creating dependency but it doesnt address the root cause, which is redox signaling disruption from excessive gut glutathione exposure
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Li, P., Yin, Y., Li, D., et al
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10.1016/j.pharmthera.2025.108861 9 AslamH.AlbaqamiF.RehmanN
